SageGuard-PC

The powerful skin defender

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SageGuard-PC is a highly concentrated standardized phytocomplex of meristematic cells of Salvia  officinalis titrated in total polyphenols expressed rosmarinic acid equivalent.

claims suggestions

  • Prevention of skin disorders caused by microbial contaminations, like dandruff, seborrheic dermatitis and sweet odour in armpit
  • Protection against damage induced by oxidative stress
  • Microbioma rebalancing in the irritated scalp
  • Microflora friendly in intimate hygiene

mechanism of action

Corynebacteria and Staphylococci are the principal bacteria that populate human armpit skin. Rosmarinic acid is efficacy against both Corynebacteria and Staphilococci, acting with antimicrobial and antiodour activity.

in vitro testing

  • Antioxidant activity (ROS inhibition, DPPH assay)
  • Antimicrobial activity (ISO 11930:2019)
  • Maintenance of skin microbiota (inoculation with lactobacillus spp.)

in vivo testing

  • Deodorant activity
  • Purifying action of the scalp thanks to a microbiome rebalancing action (Seborrhea, dandruff, eritema and itching reduction; rebalancing of distribution of dominant phylum in scalp)

Deodorant activity

  • 10 volunteers aged between 22 and 55 years
  • Treatment 0,5% SageGuard-PC was applied once a day for three days in the morning after normal cleansing and only on one armpit (the subjects did not apply any other deodorant products the day before the start of the test and did not apply any cosmetic products, including fragrance, on the untreated armpit during the duration of the test
  • The volunteers completed a self-assessment questionnaire

The application of a deodorant product with 0,5% SageGuard-PC guaranteed the absence of perceived bad odours for the 24 hours following  a single application per day for 3 days and gave a good sensation of dryness and  freshness without any kind of adverse effects.

product specification

The Mother Plant of Salvia officinalis, capable of generating specific substances useful for its growth and development within an ideal phytocomplex, is carefully selected and certified by DNA fingerprint technique.

The genus name Salvia derives from the Latin ‘salvere’ that means ‘to save’. According to popular traditions it was common to rub sage leaves on the teeth for oral cleaning, while to limit sweating of the feet it was recommended to put sage leaves in shoes.

INCI Salvia Officinalis Callus Lysate
Content of active compounds Total polyphenols expressed as rosamrinic acid equivalent ≥ 10% W/W by UPLC-DAD
Appearance Light brown powder, characteristic odour
Concentration use Starting at 0,1% W/W

lymph science: the sage without odour

Terpenes are qualitatively and quantitatively the major chemical group of the identified aroma compounds in Salvia officinalis, followed by esters. The main terpene compound is eucalyptol (1,8-cineole) and among esters linalyl acetate. Aromatic compounds, such as essential oils, are produced by specialized mature cells of the plant and therefore meristematic cells do not produce these molecules. SageGuard-PC is a phytocomplex of Salvia officinalis without odour.

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personal care